Celine Gubser is a renowned figure in the field of immunology and HIV research, with a strong background in studying immune checkpoint blockade and its implications in HIV infection. As a Senior Staff Scientist at CHUV (Centre Hospitalier Universitaire Vaudois) in Lausanne, Switzerland, Dr. Gubser has made significant contributions to the understanding of immune responses in individuals living with HIV.
Dr. Celine Gubser's research focuses on the impact of immune checkpoint blockade in HIV, particularly in relation to CD8 T cell function. Her work has shed light on how the activation of immune checkpoints can affect the immune response against HIV, providing valuable insights for the development of novel therapeutic strategies.
One of Dr. Gubser's key findings is related to GITR activation ex vivo, which has been shown to impair CD8 T cell function in individuals with HIV. This discovery has important implications for the design of immunotherapies aimed at enhancing the immune response against HIV and improving treatment outcomes for patients.
In addition to her work on immune checkpoint blockade, Dr. Celine Gubser has also developed protocols for measuring killing capacity and intracellular cytokine production in immune cells. These protocols have become valuable tools for researchers studying immune responses in various disease settings, including HIV infection.
Dr. Celine Gubser's expertise and dedication to advancing our understanding of the immune response in HIV have earned her recognition in the scientific community. Her contributions have paved the way for new avenues of research and have the potential to impact the development of more effective treatments for individuals living with HIV.
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